Todd V. Brennan, M.D., M.S.
Clinical Instructor of Surgery
Education
- University of California, Los Angeles, B.S. in Biochemistry, 1989-94
- University of California, Los Angeles, M.S. in Biochemistry, 1993-94
- Harvard, Boston, MA, M.D., 1994-99
Residencies
- University of California, San Francisco, CA., Intern, General Surgery, 1999-00
- Universitiy of California, San Francisco, CA, Resident, General Surgery, 2000-06
- University of California, San Francisco, CA, Chief Resident, General Surgery, 2006-07
Fellowships
- University of California, San Francisco, CA, Fellow, Clinical Transplantation, 2007-09
Postdoctoral Training
- University of California, San Francisco, CA, Transplantation Research, Laboratory of Dr. Sang-Mo Kang, 07/2002-06/05
Board Certification
Program Affiliations
Clinical Expertise
- Kidney Transplantation
- Liver Transplantation
- Pancreas Transplantation
Research Interests
- Allospecific T Cell Response
- Clinical Transplantation Outcomes
- Transplant Immunology
Website LInks
Biography
Dr. Todd Brennan completed a master's degree in biochemistry at the University of California, Los Angeles in 1994. He then earned his medical degree from Harvard University's School of Medicine in 1999. As part of his training he spent one year at Massachusetts General Hospital doing research in immunology and molecular biology with Dr. Brian Seed. In 2007, he completed his surgical residency at the University of California, San Francisco. During his residency, he worked in the UCSF transplant laboratory with Dr. Sang-Mo Kang investigating the allospecific T cell response. Dr. Brennan is the recipient of the American College of Surgeons Research Fellowship, the American Society of Transplant Surgeons (ASTS) Roche Laboratories Scientist Scholarship, and the ASTS Novartis Fellowship in Transplantation Award. In addition, the American Transplant Congress awarded him its Young Investigator Award for research into factors affecting early kidney graft function. Dr. Brennan currently does clinical outcome research with Dr. Sandy Feng and is investigating the fetal-maternal immune barrier with Dr. Sang-Mo Kang. He will complete his transplant fellowship with the Division of Transplantation at UCSF in June of 2009.
Selected Publications
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Brennan TV, Hoang V, Garrod KR, Liu FC, Hayden T, Kim J, Kang SM. A New T-Cell Receptor Transgenic Model of the CD4+ Direct Pathway: Level of Priming Determines Acute Versus Chronic Rejection. Transplantation. 2008 Jan 27;85(2):247-55.
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Brennan TV, Bostrom A, Tomlanovich SJ, Feng S. Optimizing living donor kidney graft function by donor-recipient pair selection. Transplantation 2006 Sep 15;82(5):651-6.
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Brennan TV, Vincenti F, Chang CK, Bostrom A, Zlatunich JK, Fuller TF, Tomlanovich SJ, Feng S. Living donor kidney transplant recipients and clinical trials: participation profiles and impact on post-transplant care. Am J Transplant 2006 Oct;6(10):2429-35.
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Brennan TV, Freise CE, Fuller TF, Bostrom A, Tomlanovich SJ, Feng S. Early graft function after living donor kidney transplantation predicts rejection but not outcomes. Am J Transplant. 2004 Jun;4(6):971-9.
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Xavier R, Brennan T, Li Q, McCormack C, Seed B. Membrane compartmentation is required for efficient T cell activation. Immunity 1998;8(6):723-732.
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