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John P. Roberts, M.D.

Professor & Chief,
Division of Transplant Surgery

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Transplant Surgery »  Faculty »  Parsia A. Vagefi

Parsia A. Vagefi, M.D.

Clinical Instructor of Surgery

Contact Information

(415) 353-1888 Clinical, Liver
(415) 353-1551 Clinical, Kidney and Pancreas
(415) 353-8725 Academic
parsia.vagefi@ucsfmedctr.org

Education

  • BA from Johns Hopkins University, 1998
  • MD from Yale School of Medicine, 2004
  • General Surgery Residency, Massachusetts General Hospital, 2009

Residencies

  • Massachusetts General Hospital, Boston, MA; General Surgery Residency.

Fellowships

  • University of California, San Francisco, CA, Fellow, Clinical Transplantation, 2009-2011

Postdoctoral Training

Board Certification

Program Affiliations

Clinical Expertise

  • Kidney Transplantation
  • Liver Transplantation
  • Pancreas Transplantation

Research Interests

Website LInks

Biography

Dr. Parsia A. Vagefi graduated with a B.A. in Biology from the Johns Hopkins University in 1998. He then earned his medical degree in 2004 from the Yale School of Medicine. During medical school he was awarded a Howard Hughes Medical Institute Research Fellowship at the Transplantation Biology Research Center of the Massachusetts General Hospital, where he studied large animal models of allograft and xenograft tolerance with Dr. David Sachs. This work led to Dr. Vagefi being awarded the Young Investigator Award from the American Transplant Congress in 2003 for his work in thymic transplantation for tolerance induction. Prior to arriving within the Division of Transplant Surgery at UCSF, Dr. Vagefi completed his surgical residency at the Massachusetts General Hospital in 2009. Dr. Vagefi has been awarded the ASTS Novartis Fellowship in Transplantation Award for his clinical research in recipients of Simultaenous Liver-Kidney transplants with Dr. Sandy Feng. He will complete his transplant fellowship in June of 2011.

Selected Publications

  1. N. Kumagai, J.C. LaMattina, C. Kamano, P.A. Vagefi, R.N. Barth, J. J. O'Neil, S.Yamamoto, S.G. Moran, R. Utsugi, D.H. Sachs, and K.Yamada. Vascularized islet cell transplantation in miniature swine: islet-kidney allografts correct the diabetic hyperglycemia induced by total pancreatectomy. Diabetes, 51(11):3220-3228, November 2002.
  2. A. Wu, K. Yamada, F.L. Ierino, P.A. Vagefi, D.H. Sachs. Regulatory mechanism of peripheral tolerance: in vitro evidence for dominant suppression of host responses during the maintenance phase of tolerance to renal allografts in miniature swine. Transplant Immunology, 11(3-4):367-374, July - September 2003.
  3. C. Kamano, P.A. Vagefi, N. Kumagai, S. Yamamoto, R.N. Barth, J.C. LaMattina, S.G. Moran, D.H. Sachs, and K. Yamada. Vascularized thymic lobe transplantation in miniature swine: II. Vascularized thymic lobe allografts support thymopoiesis and induce tolerance across a fully MHC mismatched barrier. Proceedings of the National Academy of Sciences, vol. 101, no. 11: 3827-3832, March 16, 2004.
  4. P.A. Vagefi, F.L. Ierino, P.R. Gianello, A. Shimizu, C. Kamano, D.H. Sachs, and K. Yamada. Role of the thymus in transplantation tolerance in miniature swine. IV. The thymus is required during the induction phase, but not the maintenance phase, of renal allograft tolerance. Transplantation,77(7): 979-985, April 15, 2004.
  5. K. Yamada, K. Yazawa, A. Shimizu, T. Iwanaga, Y. Hisashi, M. Nuhn, P. O'Malley, S. Nobori, P.A. Vagefi, C. Patience, J. Fishman, D.K.C. Cooper, R. J. Hawley, J. Greenstein, H.J. Schuurman, M. Awwad, M. Sykes, and D.H. Sachs. Marked prolongation of porcine renal xenograft survival in baboons through the use of alpha-1,3-galactosyltransferase gene-knockout donors and the co-transplantation of vascularized thymic tissue. Nature Medicine 11(1):32-4, January 2005.

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