Ryutaro Hirose is a Professor of Clinical Surgery at UCSF and performs liver, kidney and pancreas transplants. After graduating from Columbia College of Physicians and Surgeons, he completed his clinical and research training at UCSF as a resident in general surgery as well as a fellow in molecular medicine and transplantation surgery. His research interests include renal and hepatic ischemia - reperfusion injury, immune monitoring and skin cancer in transplant recipients. He has received funding from the NIH, NKF, UCSF, ASTS, and private industry. He is also actively involved with teaching students and residents. Dr. Hirose is currently the Associate Program Director for the General Surgery Residency at UCSF.
Dr. Hirose's research focus is ischemia-reperfusion injury and potential interventions to ameliorate renal and hepatic I-R injury. His group uses animal models, performs clinical and translational research as well as research on deceased donors. He collaborates with Dr. Claus Niemann, MD from the Dept. Anesthesia and they are co-Directors of the Ischemic Organ Injury Lab.
Three years ago, Alfonso Garcia was diagnosed with Wilson's disease and was in desperate need of a liver transplant. George Becker, who signed up to be an organ donor on his driver's license when he was 16, ended up being the right match. Garcia's UCSF medical team - which included transplant surgeon Ryutaro Hirose, MD (pictured first); Philip Rosenthal, MD (pictured second), medical director of the Pediatric Liver Transplant Program; Emily Perito, MD, a clinical fellow in pediatrics and gastroenterology; and nurse practitioner Susan Diaz, MSN - performed a successful transplant.Since receiving the liver transplant, Garcia has made it a mission to spread the word about the value of organ donation by sharing the memory of his hero, George Becker, who died after a bad sinus infection spread to his brain. As part of that mission, Garcia was selected by UCSF and the California Transplant Donor Network to ride on the Donate Life "Journeys of the Heart" float at the 2013 Tournament of Roses Parade in Pasadena, Calif., on Tuesday, Jan. 1., in honor of Becker. The float will bear a florograph of Becker - a portrait made of flowers.
"Neither man had a donor who was a match. But each had a family member willing to donate a kidney to a stranger, allowing them all to be part of chain which would, in turn, give Baty and Cienfuegos kidneys from other strangers. With 17 participating hospitals in 11 states, the chain consisted of 30 people willing to give up their kidney, matched with 30 more who needed one to survive. UCSF surgeons Andrew Posselt, M.D., Ph.D. and Ryutaro Hirose, M.D., performed the transplants on Baty and Cienfuegos - just two of the 300 or so kidney transplants performed at UCSF every year."
Claus Niemann, MD, Associate Professor in the UCSF Department of Anesthesia and Perioperative Care and co-Director of the Ischemic Organ Injury Lab (pictured left), has been awarded a $2 million grant by the Health Resources and Services Administration (HRSA) to improve outcomes in organ donor transplantation. The grant award also included collaborators John Feiner, MD, Ryutaro Hirose, MD, and John Roberts, MD, chief of the UCSF Division of Transplant Surgery, the California Transplant Donor Network and Darren Malinoski, MD, of Cedars-Sinai Medical Center in Los Angeles. The innovative project is designed to determine the optimal management of organ donors before the procurement operation occurs. Research in this area has been hindered by numerous obstacles including the logistical challenges of conducting research in large hospitals in California and northern Nevada.
"Alfonso Garcia, the son of a respiratory therapist at UCSF Medical Center, was a typical, healthy 15-year-old when he started feeling sick ─ feverish, anemic, fatigued and jaundiced. Alfonso learned he had Wilson's disease, a rare genetic disorder in which copper isn't properly eliminated from the body and damages the liver and nervous system. He and his family received a grave prognosis. He had just 48 hours to find a liver transplant or he might not survive. With the help of Philip Rosenthal, M.D., (left) a pediatric liver specialist, and Ryutaro Hirose, M.D. (right), an organ transplant surgeon, Alfonso received a successful, emergency liver transplant. The donor was another young man, a 22-year-old from Sacramento who had lost his life suddenly due to a sinus infection that had spread to his brain."
"Previously, Uruguay had tried to go it alone, but high mortality rates soon caused doctors to shut the program down. After their initial visit, the UCSF transplant team, including anesthesiologist Claus Niemann, MD (pictured first), and surgeons Ryutaro Hirose, MD (pictured second), and Peter Stock, MD, PhD, (pictured third) continued to consult with the team in Uruguay, guiding them through everything from patient selection procedures to the use of immunosuppressive medications following surgery. When it came time for Uruguayan doctors to conduct their first liver transplant since revamping the program, UCSF doctors oversaw the operation by dialing in via Skype."
"The next day, surgeons at the University of California at San Francisco performed a rare liver transplant called a ``domino transplant,'' the first in the Bay Area and one of just a handful done in the United States. ........................Her choice was to have a liver that will give her a disease in 30 years, or die of cancer in the next year,'' said Dr. Ryutaro Hirose (pictured left), the surgeon for both transplants. ``She jumped at the chance, and most people would.''