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Linda D. Ferrell, MD

Linda D. Ferrell, MD

Emeritus Professor
Departments of Pathology & Laboratory Medicine 

Contact Information

Fax: 415-353-1200
Department of Pathology
505 Parnassus Ave., Rm. M590, Box 0102
San Francisco, CA 94143
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  • 1970-74 University of Kansas, Lawrence, KS B.A. Summa cum laude, Microbiology
  • 1974-77 University of Kansas, Kansas City, KS M.D.
  • 1977-79 University of Kansas, Kansas City, KS Resident Pathology
  • 1980-81 University of California, San Francisco Chief Resident/Surgical Pathology Fellow, Pathology
  • American Board of Pathology, Anatomic Pathology
  • Member, UCSF Helen Diller Family Comprehensive Cancer Center
  • UCSF Medical Center Organ Transplant Program
  • Fatty liver
  • Hepatitis B and C
  • Liver pathology, emphasizing liver transplantation
  • Liver tumors
  • Well-differentiated hepatocellular tumors & vascular lesions

Linda Ferrell, M.D. is a liver pathologist, Professor of Pathology, Vice Chair of Clinical Services, and Director of Surgical Pathology at UCSF. She specializes in the diagnosis of liver disorders such as: benign liver tumors, cirrhosis, hepatitis B, hepatitis C, hepatocellular carcinoma, vascular lesions, metastastic cancer to the liver, liver transplantation, nonalcoholic fatty liver disease (NAFLD) and nonalcoholic steatohepatitis (NASH). She graduated summa cum laude from the University of Kansas, where she also attended medical school and completed her residency. Dr. Ferrell went on to complete her surgical pathology fellowship at the University of California, San Francisco, while concurrently serving as Chief Resident. She has been the recipient of numerous awards, published a large number of articles and book chapters and currently serves as a co-editor on two medical textbooks in her field of expertise. In early 2010 she was elected Vice President of the United States and Canadian Academy of Pathology (USCAP). Information pertaining to her awards and published materials can be found on her Curriculum Vitae.

Dr. Ferrell's research interests are primarily liver pathology, with emphasis on liver transplantation, fatty liver, hepatitis B and C and liver tumors, particularly well-differentiated hepatocellular tumors and vascular lesions. She actively participated in the World Congress' Consensus Groups for the nomenclature of nodules in the liver and recommendations for terminology for hepatic allograft rejection. Dr. Ferrell's studies on liver pathology in recurrent hepatitis C after transplantation and on the diagnosis of dysplastic nodules have been recognized internationally as leading papers ion these topics. She was also involved in a recent evaluation and review of benign liver tumors in coordination with the International Liver Pathology Study Group and the Laennec Society. Her current ongoing studies involve unusual variants of tumors (HCC, vascular, others), vascular malformations in the liver and other markers in well-differentiated hepatocellular tumors.

Most recent publications from a total of 71
  1. Guido M, Alves VA, Balabaud C, Bathal PS, Bioulac-Sage P, Colombari R, Crawford JM, Dhillon AP, Ferrell LD, Gill RM, Hytiroglou P, Nakanuma Y, Paradis V, Quaglia A, Rautou PE, Theise ND, Thung S, Tsui WM, Sempoux C, Snover D, van Leuwen DJ. Histology of portal vascular changes associated with idiopathic non-cirrhotic portal hypertension: nomenclature and definition. Histopathology. 2018 Aug 21. View in PubMed
  2. Joseph NM, Brunt EM, Marginean C, Nalbantoglu I, Snover DC, Thung SN, Yeh MM, Umetsu SE, Ferrell LD, Gill RM. Frequent GNAQ and GNA14 Mutations in Hepatic Small Vessel Neoplasm. Am J Surg Pathol. 2018 Jul 03. View in PubMed
  3. Kakar S, Ferrell LD. Glutamine synthetase staining and CTTNB1 mutation in hepatocellular adenomas. Hepatology. 2017 12; 66(6):2092-2093. View in PubMed
  4. Graham RP, Yeh MM, Lam-Himlin D, Roberts LR, Terracciano L, Cruise MW, Greipp PT, Zreik RT, Jain D, Zaid N, Salaria SN, Jin L, Wang X, Rustin JG, Kerr SE, Sukov WR, Solomon DA, Kakar S, Waterhouse E, Gill RM, Ferrell L, Alves VA, Nart D, Yilmaz F, Roessler S, Longerich T, Schirmacher P, Torbenson MS. Molecular testing for the clinical diagnosis of fibrolamellar carcinoma. Mod Pathol. 2018 Jan; 31(1):141-149. View in PubMed
  5. Tsai JH, Ferrell LD, Tan V, Yeh MM, Sarkar M, Gill RM. Aggressive non-alcoholic steatohepatitis following rapid weight loss and/or malnutrition. Mod Pathol. 2017 Jun; 30(6):834-842. View in PubMed
  6. Deniz K, Moreira RK, Yeh MM, Ferrell LD. Steatohepatitis-like Changes in Focal Nodular Hyperplasia, A Finding to Distinguish From Steatohepatitic Variant of Hepatocellular Carcinoma. Am J Surg Pathol. 2017 Feb; 41(2):277-281. View in PubMed
  7. Balitzer D, Shafizadeh N, Peters MG, Ferrell LD, Alshak N, Kakar S. Autoimmune hepatitis: review of histologic features included in the simplified criteria proposed by the international autoimmune hepatitis group and proposal for new histologic criteria. Mod Pathol. 2017 May; 30(5):773-783. View in PubMed
  8. Ehman EC, Umetsu SE, Ohliger MA, Fidelman N, Ferrell LD, Yeh BM, Yee J, Hope TA. Imaging prediction of residual hepatocellular carcinoma after locoregional therapy in patients undergoing liver transplantation or partial hepatectomy. Abdom Radiol (NY). 2016 Nov; 41(11):2161-2168. View in PubMed
  9. Cuervo H, Nielsen CM, Simonetto DA, Ferrell L, Shah VH, Wang RA. Endothelial notch signaling is essential to prevent hepatic vascular malformations in mice. Hepatology. 2016 10; 64(4):1302-1316. View in PubMed
  10. Tsokos CG, Krings G, Yilmaz F, Ferrell LD, Gill RM. Proliferative index facilitates distinction between benign biliary lesions and intrahepatic cholangiocarcinoma. Hum Pathol. 2016 11; 57:61-67. View in PubMed
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