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Jennifer C. Lai, M.D., M.B.A.

Jennifer C. Lai, M.D., M.B.A.

Assistant Professor of Medicine
General Hepatology and Liver Transplantation
Department of Medicine

Contact Information

Academic Office
Division of Gastroenterology
513 Parnassus Avenue, Room S-357
San Francisco, CA 94143-0358
(415) 476-6422 - Phone
(415) 476-0659 - Fax
Jennifer.Lai@ucsf.edu
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  • Stanford University, BS, Biology, 1996-2000
  • Tufts University School of Medicine, MD, MBA, 2001-2005
  • New York Presbyterian Hospital-Columbia, Intern, Internal Medicine, 2005-2006
  • New York Presbyterian Hospital-Columbia, Resident, Internal Medicine, 2006-2008
  • University of California, San Francisco, Fellow, Gastroenterology, 2008-2011
  • University of California, San Francisco, Fellow, Transplant Hepatology, 2011-2012
  • University of California, San Francisco, Advanced Training in Clinical Research, 2009-2010
  • American Board of Internal Medicine
  • American Board of Internal Medicine - Gastroenterology
  • UCSF Liver Center
  • Hepatitis C virus (HCV)
  • Impact of function status in patients on the liver-transplant waiting list
  • Patterns of donor liver allocation and liver transplant outcomes

Dr. Jennifer C. Lai is a general and transplant hepatologist, specializing in treating patients with chronic viral hepatitis (both B and C), autoimmune disorders, and those with end-stage liver disease needing liver transplantation. 

After earning her undergraduate degree from Stanford University and combined MD/MBA degrees from Tufts University, she completed residency at the New York Presbyterian Hospital-Columbia and gastroenterology and advanced/transplant hepatology fellowships at UCSF. She is a member of the American Association for the Study of Liver Diseases, American Society of Transplantation, American Gastroenterological Association, and American College of Gastroenterology. She has been recognized as a Fellow of the American College of Physicians (FACP). Dr. Lai is board certified in Internal Medicine and Gastroenterology. 

  • Floyd Rector Internal Medicine Research Mentoring Award, UCSF, 2019
  • Fellow, American Society of Transplantation, 2017
  • AST/Novartis Faculty Development Award (grant), American Society of Transplantation, 2016-2017
  • Clinical Science Career Development Award, American Society of Transplantation, 2016
  • New Investigator Award, American Geriatrics Society, 2015
  • Young Investigator Award, International Liver Transplantation Society, 2015
  • Paul B. Beeson Scholar in Aging Research (grant), American Federation for Aging Research, 2014-2019
  • Associate Scholar Genius Award (grant), UCSF Pepper Center, 2014-2015
  • T. Franklin Williams Scholar (grant), Association of Specialty Professors, 2013-2015
  • Pilot/Feasibility Award (grant), UCSF Liver Center, 2013-2014
  • Pilot Award in Aging Research (grant), UCSF Pepper Center, 2013-2014
  • Pilot for Junior Investigator Award (grant), UCSF Resource Allocation Program, 2013-2014
  • Fellow, American College of Physicians, 2012-curr
  • Junior Faculty Career Development Award (grant), American College of Gastroenterology, 2012-2015
  • Transplant Hepatology Fellowship (grant), American Association for the Study of Liver Diseases, 2011-2012
  • Clinical Research Award (grant), American College of Gastrenterology, 2011-2012
  • Vanguard Award, International Liver Transplantation Society, 2011
  • Sylvia Allison Kaplan Clinical Research Award (grant), Northern California Kaiser Permanente, 2009-2010
  • Alpha Omega Alpha, Tufts University School of Medicine, 2005
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Dr. Lai has engaged in research investigating clinical outcomes in patients with chronic liver disease. Her research focuses on three main areas:

1) Understanding the impact of functional status and physiologic reserve (i.e., frailty) in patients with cirrhosis awaiting liver transplantation (actively enrolling)

2) Evaluating the association between chronic hepatitis C and systemic inflammation with Vitamin D status and bone mineral density (actively enrolling)

3) Characterizing patterns of liver allocation and distribution and their association with liver transplant outcomes (both pre- and post-transplant) on a national level

Most recent publications from a total of 86
  1. Ge J, Lai JC. Split-Liver Allocation: An Underused Opportunity to Expand Access to Liver Transplantation. Liver Transpl. 2019 May; 25(5):690-691. View in PubMed
  2. Rubin JB, Sinclair M, Rahimi RS, Tapper EB, Lai JC. Women on the liver transplantation waitlist are at increased risk of hospitalization compared to men. World J Gastroenterol. 2019 Feb 28; 25(8):980-988. View in PubMed
  3. Rubin JB, Sundaram V, Lai JC. Gender Differences Among Patients Hospitalized With Cirrhosis in the United States. J Clin Gastroenterol. 2019 Feb 22. View in PubMed
  4. O'Leary JG, Bajaj JS, Tandon P, Biggins SW, Wong F, Kamath PS, Garcia-Tsao G, Maliakkal B, Lai J, Fallon M, Vargas HE, Thuluvath P, Subramanian R, Thacker LR, Reddy RK. Outcomes after Listing for Liver Transplant in Patients with Acute-on-Chronic Liver Failure (ACLF): The Multicenter NACSELD Experience. Liver Transpl. 2019 Feb 05. View in PubMed
  5. Cullaro G, Verna EC, Lai JC. Association Between Renal Function Pattern and Mortality in Patients with Cirrhosis. Clin Gastroenterol Hepatol. 2019 Feb 01. View in PubMed
  6. Bajaj JS, Tandon P, O'Leary JG, Wong F, Biggins SW, Garcia-Tsao G, Kamath PS, Maliakkal B, Fallon MB, Lai JC, Thuluvath PJ, Vargas HE, Subramanian RM, Thacker LR, Reddy KR. Outcomes in Patients With Cirrhosis on Primary Compared to Secondary Prophylaxis for Spontaneous Bacterial Peritonitis. Am J Gastroenterol. 2019 Jan 23. View in PubMed
  7. Haugen CE, McAdams-DeMarco M, Holscher CM, Ying H, Gurakar AO, Garonzik-Wang J, Cameron AM, Segev DL, Lai JC. Multicenter Study of Age, Frailty, and Waitlist Mortality Among Liver Transplant Candidates. Ann Surg. 2019 Jan 18. View in PubMed
  8. Lai JC, Rahimi R, Verna EC, Kappus MR, Dunn MA, McAdams-DeMarco M, Haugen CE, Volk ML, Duarte-Rojo A, Ganger DR, O'leary JG, Dodge JL, Ladner D, Segev D. Frailty Associated With Waitlist Mortality Independent of Ascites and Hepatic Encephalopathy in a Multi-Center Study. Gastroenterology. 2019 Jan 17. View in PubMed
  9. Perito ER, Bucuvalas J, Lai JC. Functional status at listing predicts waitlist and posttransplant mortality in pediatric liver transplant candidates. Am J Transplant. 2018 Dec 01. View in PubMed
  10. Kobashigawa J, Dadhania D, Bhorade S, Adey D, Berger J, Bhat G, Budev M, Duarte-Rojo A, Dunn M, Hall S, Harhay MN, Johansen KL, Joseph S, Kennedy CC, Kransdorf E, Lentine KL, Lynch RJ, McAdams-DeMarco M, Nagai S, Olymbios M, Patel J, Pinney S, Schaenman J, Segev DL, Shah P, Singer LG, Singer JP, Sonnenday C, Tandon P, Tapper E, Tullius SG, Wilson M, Zamora M, Lai JC. Report from the American Society of Transplantation on frailty in solid organ transplantation. Am J Transplant. 2018 Dec 01. View in PubMed
  11. View All Publications
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