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Jennifer C. Lai, M.D., M.B.A.

Jennifer C. Lai, M.D., M.B.A.

Assistant Professor of Medicine
General Hepatology and Liver Transplantation
Department of Medicine

Contact Information

Academic Office
Division of Gastroenterology
513 Parnassus Avenue, Room S-357
San Francisco, CA 94143-0358
(415) 476-6422 - Phone
(415) 476-0659 - Fax
Jennifer.Lai@ucsf.edu
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  • Stanford University, BS, Biology, 1996-2000
  • Tufts University School of Medicine, MD, MBA, 2001-2005
  • New York Presbyterian Hospital-Columbia, Intern, Internal Medicine, 2005-2006
  • New York Presbyterian Hospital-Columbia, Resident, Internal Medicine, 2006-2008
  • University of California, San Francisco, Fellow, Gastroenterology, 2008-2011
  • University of California, San Francisco, Fellow, Transplant Hepatology, 2011-2012
  • University of California, San Francisco, Advanced Training in Clinical Research, 2009-2010
  • American Board of Internal Medicine
  • American Board of Internal Medicine - Gastroenterology
  • UCSF Liver Center
  • Hepatitis C virus (HCV)
  • Impact of function status in patients on the liver-transplant waiting list
  • Patterns of donor liver allocation and liver transplant outcomes

Dr. Jennifer C. Lai is a general and transplant hepatologist, specializing in treating patients with chronic viral hepatitis (both B and C), autoimmune disorders, and those with end-stage liver disease needing liver transplantation. 

After earning her undergraduate degree from Stanford University and combined MD/MBA degrees from Tufts University, she completed residency at the New York Presbyterian Hospital-Columbia and gastroenterology and advanced/transplant hepatology fellowships at UCSF. She is a member of the American Association for the Study of Liver Diseases, American Society of Transplantation, American Gastroenterological Association, and American College of Gastroenterology. She has been recognized as a Fellow of the American College of Physicians (FACP). Dr. Lai is board certified in Internal Medicine and Gastroenterology. 

  • Clinical Science Career Development Award, American Society of Transplantation, 2016
  • AST/Novartis Faculty Development Award (grant), American Society of Transplantation, 2016-2017
  • New Investigator Award, American Geriatrics Society, 2015
  • Young Investigator Award, International Liver Transplantation Society, 2015
  • Associate Scholar Genius Award (grant), UCSF Pepper Center, 2014-2015
  • Paul B. Beeson Scholar in Aging Research (grant), American Federation for Aging Research, 2014-2019
  • Pilot for Junior Investigator Award (grant), UCSF Resource Allocation Program, 2013-2014
  • T. Franklin Williams Scholar (grant), Association of Specialty Professors, 2013-2015
  • Pilot/Feasibility Award (grant), UCSF Liver Center, 2013-2014
  • Pilot Award in Aging Research (grant), UCSF Pepper Center, 2013-2014
  • Fellow, American College of Physicians, 2012-curr
  • Junior Faculty Career Development Award (grant), American College of Gastroenterology, 2012-2015
  • Vanguard Award, International Liver Transplantation Society, 2011
  • Clinical Research Award (grant), American College of Gastrenterology, 2011-2012
  • Transplant Hepatology Fellowship (grant), American Association for the Study of Liver Diseases, 2011-2012
  • Sylvia Allison Kaplan Clinical Research Award (grant), Northern California Kaiser Permanente, 2009-2010
  • Alpha Omega Alpha, Tufts University School of Medicine, 2005
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Dr. Lai has engaged in research investigating clinical outcomes in patients with chronic liver disease. Her research focuses on three main areas:

1) Understanding the impact of functional status and physiologic reserve (i.e., frailty) in patients with cirrhosis awaiting liver transplantation (actively enrolling)

2) Evaluating the association between chronic hepatitis C and systemic inflammation with Vitamin D status and bone mineral density (actively enrolling)

3) Characterizing patterns of liver allocation and distribution and their association with liver transplant outcomes (both pre- and post-transplant) on a national level

Most recent publications from a total of 64
  1. Ge J, Gilroy R, Lai JC. Receipt of a pediatric liver offer as the first offer reduces waitlist mortality for adult women. Hepatology. 2018 Mar 31. View in PubMed
  2. Puchades L, Chau S, Dodson JA, Mohamad Y, Mustain R, Lebsack A, Aguilera V, Prieto M, Lai JC. Association of Cardiac Abnormalities to the Frail Phenotype in Cirrhotic Patients on the Waitlist: From the Functional Assessment in Liver Transplantation Study. Transplantation. 2018 Mar; 102(3):e101-e107. View in PubMed
  3. Reuter B, Walter K, Bissonnette J, Leise MD, Lai J, Tandon P, Kamath PS, Biggins SW, Rose CF, Wade JB, Bajaj JS. Assessment of the Spectrum of Hepatic Encephalopathy: A Multi-Center Study. Liver Transpl. 2018 Feb 19. View in PubMed
  4. Lai JC, Covinsky KE, Dodge JL, Boscardin WJ, Segev DL, Roberts JP, Feng S. Reply (to LTE HEP-17-2332). Hepatology. 2018 Jan 29. View in PubMed
  5. O'Leary JG, Reddy KR, Garcia-Tsao G, Biggins SW, Wong F, Fallon MB, Subramanian RM, Kamath PS, Thuluvath P, Vargas HE, Maliakkal B, Tandon P, Lai J, Thacker LR, Bajaj JS. NACSELD Acute-on-Chronic Liver Failure (NACSELD-ACLF) Score Predicts 30-Day Survival in Hospitalized Patients with Cirrhosis. Hepatology. 2018 Jan 08. View in PubMed
  6. Bajaj JS, Rajender Reddy K, Tandon P, Wong F, Kamath PS, Biggins SW, Garcia-Tsao G, Fallon M, Maliakkal B, Lai J, Vargas HE, Subramanian RM, Thuluvath P, Thacker LR, O'Leary JG. Prediction of Fungal Infection Development and Their Impact on Survival Using the NACSELD Cohort. Am J Gastroenterol. 2018 Apr; 113(4):556-563. View in PubMed
  7. Lai JC, Covinsky KE, McCulloch CE, Feng S. The Liver Frailty Index Improves Mortality Prediction of the Subjective Clinician Assessment in Patients With Cirrhosis. Am J Gastroenterol. 2018 Feb; 113(2):235-242. View in PubMed
  8. Cullaro G, Sarkar M, Lai JC. Sex-based disparities in delisting for being "too sick" for liver transplantation. Am J Transplant. 2017 Dec 01. View in PubMed
  9. Fleming JN, Lai JC, Te HS, Said A, Spengler EK, Rogal SS. Opioid and opioid substitution therapy in liver transplant candidates: A survey of center policies and practices. Clin Transplant. 2017 Dec; 31(12). View in PubMed
  10. Spengler EK, O'Leary JG, Te HS, Rogal S, Pillai AA, Al-Osaimi A, Desai A, Fleming JN, Ganger D, Seetharam A, Tsoulfas G, Montenovo M, Lai JC. Liver Transplantation in the Obese Cirrhotic Patient. Transplantation. 2017 10; 101(10):2288-2296. View in PubMed
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Publications provided by UCSF Profiles, powered by CTSI at UCSF. View profile of Jennifer C. Lai, M.D., M.B.A.
Please note: UCSF Profiles publications are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact CTSI for help.

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