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Garrett R. Roll, M.D., FACS

Garrett R. Roll, M.D., FACS

Assistant Professor of Surgery
Division of Transplant Surgery

Contact Information

Academic Office
(415) 353-8725
garrett.roll@ucsf.edu
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  • Boston College, BS, Finance, 1995-1999
  • Brandeis University, Post Baccalaureate, Premedical, 1999-2001
  • Temple University School of Medicine, MD, 2001-2005
  • University of California, San Francisco, General Surgery, 2005-2012
  • UCSF Department of GI Hepatology Research Fellowship
  • University of California, San Francisco, Abdominal Transplant Surgery, 2012-2014
  • Senior international Fellow in liver transplant and retrieval, Queen Elizabeth Hospital, Birmingham, England
  • American Board of Surgery, General Surgery
  • Transplantation
  • HBP surgery
  • Ascites
  • Bile Duct Cancer (Cholangiocarcinoma)
  • Bile Duct Injuries
  • Bile Duct Strictures
  • Bridging Therapies to Downstage HCC in Liver Transplant Setting
  • Choledochal Cysts
  • Deceased Donor Organ Utilization
  • Gallbladder Cancer
  • Hepatocellular Carcinoma (Primary Liver Cancer)
  • Kidney Transplantation
  • Laparoscopic Donor Nephrectomy
  • Liver Biopsy
  • Liver Cysts
  • Liver Metastases (Secondary Liver Cancer)
  • Liver Resection
  • Liver Transplantation
  • Living Donor Kidney Transplantation
  • Living Donor Liver Transplantation
  • Normothetic Machine Liver Perfusion
  • Organ Donation of Cardiovascular Death
  • Pancreas Transplantation
  • Pediatric Kidney Transplantation
  • Pediatric Liver Transplantation
  • Portal Hypertension
  • Cell therapy with hepatocytes and hepatocyte-like cells derived from stem cells.
  • Normothetic machine liver perfusion
  • Role of miRNA in liver regeneration

Dr. Roll is a general surgeon specializing in abdominal organ transplantation. He completed both general surgery training and the abdominal organ transplant fellowship at the University of California San Francisco. 

During his training, Dr. Roll spent 2 years in Dr. Holger Willenbring's laboratory investigating stem cell biology in the context of liver cell therapy, as well as normal and pathologic liver regeneration. His research concentrated on the use of hepatocyte-like cells derived from stem cells to be used in liver cell therapy. In particular, Dr. Roll investigated the regenerative capabilities of hepatocytes derived from induced pluripotent stem (iPS) cells. They used a genetically deficient mouse model of liver disease as a way to test the functional capabilities of these cells after transplantation. They were able to demonstrate that the profound proliferative capabilities of adult hepatocytes are retained by hepatocytes derived from iPS cells, and transplanting these cells rescued mice with liver failure. Dr. Roll also investigated the role of miRNA in liver regeneration, and the rejection of transplanted hepatocytes and hepatocyte-like cells. The principles of his research will remain valuable in liver and pancreas cell therapy translational science for years.

After fellowship Dr. Roll moved to England to become a Senior International Fellow in Liver Transplant and Multi Organ Procurement at Queen Elizabeth Hospital, Birmingham, one of the busiest liver transplant departments in the United Kingdom. There he gained valuable experience in the blossoming field of normothermic machine liver perfusion prior to returning to UCSF. 

Most recent publications from a total of 40
  1. Braun HJ, Dodge JL, Grab JD, Syed SM, Roll GR, Freise CE, Roberts JP, Ascher NL. Living Donor Liver Transplant for Alcoholic Liver Disease: Data from the Adult to Adult Living Donor Liver Transplantation Study (A2ALL). Transplantation. 2019 May 15. View in PubMed
  2. Feinstein MA, Marcus SG, Amara DP, Durcanova B, Roll GR, Orandi BJ. The effect of an organ procurement experience on preclinical medical student perceptions of transplant surgery. Clin Transplant. 2019 Apr; 33(4):e13505. View in PubMed
  3. Gao Y, Twigg AR, Hirose R, Roll GR, Nowacki AS, Maytin EV, Vidimos AT, Rajalingam R, Arron ST. Association of HLA Antigen Mismatch With Risk of Developing Skin Cancer After Solid-Organ Transplant. JAMA Dermatol. 2019 Jan 23. View in PubMed
  4. Adelmann D, Roll GR, Kothari R, Syed S, Burdine LJ, Tavakol M, Niemann CU. The Impact of Deceased Donor Liver Extraction Time on Early Allograft Function in Adult Liver Transplant Recipients. Transplantation. 2018 Nov; 102(11):e466-e471. View in PubMed
  5. Juszczak H, Lowenstein SE, Crow L, Roll GR, McCalmont TH, Arron ST. Potential for overlooked melanoma in solid organ donors with a severely dysplastic nevus. JAAD Case Rep. 2018 Aug; 4(7):682-683. View in PubMed
  6. Adelmann D, Olmos A, Liu LL, Feiner JR, Roll GR, Burdine L, Tavakol M, Syed S, Orandi BJ, Niemann CU. Intraoperative Management of Liver Transplant Patients Without the Routine Use of Renal Replacement Therapy. Transplantation. 2018 05; 102(5):e229-e235. View in PubMed
  7. Perito ER, Roll G, Dodge JL, Rhee S, Roberts JP. Split Liver Transplantation and Pediatric Waitlist Mortality in the United States: Potential for Improvement. Transplantation. 2019 Mar; 103(3):552-557. View in PubMed
  8. Adelmann D, Bicknell L, Niemann CU, Feiner J, Roll GR, Burdine L, Whitlock EL. Central venous pressure monitoring in living donor kidney recipients does not affect immediate graft function: A propensity score analysis. Clin Transplant. 2018 May; 32(5):e13238. View in PubMed
  9. Mergental H, Roll GR. Normothermic machine perfusion of the liver. Clin Liver Dis (Hoboken). 2017 Oct; 10(4):97-99. View in PubMed
  10. Harbell JW, Morgan T, Feldstein VA, Roll GR, Posselt A, Kang SM, Feng S, Hirose R, Freise CE, Stock P. Splenic Vein Thrombosis Following Pancreas Transplantation: Identification of Factors That Support Conservative Management. Am J Transplant. 2017 Nov; 17(11):2955-2962. View in PubMed
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Publications provided by UCSF Profiles, powered by CTSI at UCSF. View profile of Garrett R. Roll, M.D., FACS
Please note: UCSF Profiles publications are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact CTSI for help.

 

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